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Study 3: IV safety (2025)

c-Myc directly activates the genes involved in nucleotide synthesis, including thymidylate synthase for pyrimidine metabolism, inosine monophosphate dehydrogenase 1 and 2 for purine metabolism, and phosphoribosyl pyrophosphate (PRPP) synthetase 2 for the production of PRPP, which is a common precursor for purine and pyrimidine nucleotides

Each route has advantages and limitations

Ghafouri-Fard S, Shoorei H, Taheri M (2020) Role of non-coding RNAs in the pathogenesis of endometriosis

A confidence interval needs to be computed for each parameter estimate because this allows to obtain a range for the parameter estimate, which gives an indication about the uncertainty of the parameter value taking into account the quantity and variability of the data

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