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When an E/M visit is billed on the same day as an IV iron infusion, Modifier 25 is required on the E/M code to indicate a significant, separately identifiable evaluation and management service

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Route-Specific Pharmacokinetics: Intravenous Route:Peak plasma levels of cyanocobalamin are attained within 1 hour for parenteral doses

Document IENFD result (fibers/mm), skin biopsy site, and diagnosis statement to support specificity