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Unfortunately, in a phase III trial of METIV-HCC, tivantinib did not improve overall patient survival compared to the placebo (Rimassa et al., 2018)

10.1016/j.ecoenv.2023.114714 74

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When to Talk to a Provider You should consult a qualified provider if you experience: Persistent side effects beyond two weeks Increasing swelling or discomfort Changes in blood sugar or energy that feel abnormal Any symptom that causes concern Often, small adjustments can significantly improve tolerability