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Anaphylactic shock and death have been reported after parenteral vitamin B 12 administration

AOD9604:

If injection volume is a limiting factor, rotate injection sites and administer compounds sequentially at different sites rather than combining them in one syringe

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Risks and Side Effects While B12 shots are generally very safe, you should be aware of a few risks: Injection Site Pain: You might feel mild soreness or see redness where the shot was given

What needle size is appropriate for subcutaneous AHK-Cu injection