Primary endpoints should center on pain and function Knee Injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Patient-Reported Outcome Measurement Information System (PROMIS) scores), structure (MRI evaluation with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) when appropriate), and time to milestones (return to sport)
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However, for patients without a true vitamin B12 deficiency, research shows that B12 injections are unlikely to boost energy or reduce fatigue
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Use it within 28 days, the window supported by the antimicrobial preservative in bacteriostatic water
Its already a popular ingredient in topical skin and haircare products, with manufacturers claiming it can do everything from reducing fine lines and fading hyperpigmentation to tightening loose skin