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Immunogenicity The ability of a foreign substance, such as a viral or non-viral vector, to provoke an undesirable immune response, which can lead to reduced efficacy of the drug, allergic reactions or other adverse reactions

doi: 10.1124/jpet.115.230201

M., Lynch, B

Subsequent studies confirmed that DSIP promotes the onset and duration of delta sleep the deep, restorative phase of the sleep cycle associated with tissue repair, growth hormone release, and memory consolidation rather than simply inducing sedation

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Innovative approaches, including nanocarrier-based drug delivery platforms and prodrug strategies, are emerging as promising solutions to enhance the pharmacological performance of ferroptosis inhibitors and inducers, potentially bridging the gap between experimental efficacy and clinical application