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Strate LL, Liu YL, Huang ES, Giovannucci EL, Chan AT

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The combined use of Nm with 2F-, 2O-methoxy modifications, or phosphorothioate linkages reduced protein expression in cell lysates, yet such modified mRNA was still five times more efficient than unmodified RNA

Oxidative stress occurs when the body does not have ample antioxidant fighting power to combat free radicals

For anti-aging and longevity optimization, the priority shifts from acute metabolic correction to long-term mitochondrial maintenance and senescence suppression