Vegans, vegetarians, older adults, and people with digestive conditions such as Crohns disease or coeliac disease are at higher risk, according to the NHS
By inhibiting the NNMT enzyme, it prevents the excessive consumption of NAD+, a critical molecule that your cells need for energy production, DNA repair, and maintaining healthy metabolic function
Along with the increase in energy will likely be the increase in cognitive functioning, so you may notice an improvement in your memory and quality of sleep around the same time as the reduction in fatigue
Other causes involve multiple sclerosis, stroke, and brain damage, among others
Dosing Protocol Suggested approach for the 50 mg vial format
Couture Med Spa reports a similar pattern among its own tirzepatide and semaglutide patients, listing mild nausea or upset stomach, temporary irritation at the injection site, fatigue or headaches, and changes in appetite, and adds that most side effects fade as the body adjusts to treatment (couturemedspa.com)