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Small-molecule inhibitors of glutathione S-transferase P1-1 as anticancer therapeutic agents

BMC Genomics 18:266

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Inhibition of tubular cell proliferation by neutralizing endogenous HGF leads to renal hypoxia and bone marrow-derived cell engraftment in acute renal failure

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3,4 In addition to their antitumour effects, ICIs have been reported to cause characteristic adverse events, called immune-related adverse events (irAEs), 5 in the lung, skin, gastrointestinal tract, liver and endocrine glands