Potential Side Effects While rare, some individuals may experience the following side effects after receiving glutathione injections: Bloating and Cramping: Some people may experience gastrointestinal discomfort, such as bloating and cramping
Systemic bias of cytokine production toward cell-mediated immune regulation in IDDM and toward humoral immunity in graves' disease
Unlike apoptosis, it does not involve nuclear fragmentation, chromatin condensation, or caspase activation
How This Works Glutathione (GSH) is the bodys most abundant intracellular antioxidant, present in virtually every cell at concentrations of 110 mM [7]
Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations AML: acute myeloid leukemia AP-1: activator protein-1 ASK1: apoptosis signal-regulating kinase 1 BCNU: N,N -bis(2-chloroethyl)- N -nitrosourea CDNB: 1-chloro-2,4-dinitrobenzene CFU-GM: colony forming unit-granulocyte, monocyte DXR: doxorubicin EA: ethacrynic acid ERK: extracellular signal-regulated kinase 5-FU: 5-fluorouracil GSH: glutathione GST: glutathione S -transferase H 2 O 2 : hydrogen peroxide HEL: Haloenol lactone HFF: human foreskin fibroblast JNK: c-Jun N-terminal kinase MAPK: mitogen-activated protein kinase MAPEG: membrane-associated proteins in eicosanoid and glutathione MDS: myelodysplastic syndrome NCI: National Cancer Institute NTZ: nitazoxanide ROS: reactive oxygen species TLK117: ( -glutamyl- S -(benzyl)cysteinyl- R (-)-phenylglycine) TRAF2: TNF receptor-associated factor 2 UV: ultraviolet References Litwack G, Ketterer B, Arias IM
doi: 10.1152/physrev.00018.2001 72 DrgeW.BreitkreutzR
