for B12 deficiency, supplementation
The body can do this but many times the reason the deficiency exists is because there is some venerability with formation of methyldonors (like methylcobalmin)
These include anaphylactic shock, pulmonary edema, or congestive heart failure in susceptible individuals
The Nobel Prize in Physiology or Medicine 1934, Nobelprize.org , Nobel Media AB 2014
Intragastric application of aspirin, clopidogrel, cilostazol, and BPC 157 in rats: Platelet aggregation and blood clot
SURPASS-CVOT (N=13,165) noninferior on 3-point MACE (HR 0.92), significant on 4-point MACE (0.88) and all-cause death (0.84): Heerspink SURPASS-4 kidney post-hoc