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The reclassification does not resolve all scientific questions about these compounds the lack of large-scale human trials remains a real limitation that physicians and patients should take seriously

Clinics marketing walk-in glutathione drips without prescriber evaluation operate outside the legal framework for compounded drug administration

Conservative treatment is the first-line approach, but if physiotherapy fails, there is no consensus in the literature on further therapy

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No plant food is a reliable source of vitamin B12, except for B12-fortified products, such as plant milks, some mock meats, cereals or nutritional yeast but those alone cannot guarantee a sufficient intake (Rizzo et al., 2016)

doi: 10.1186/1741-7015-11-236 275 JiQZhangSJiangWWangJLuanYXinQ