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The USPSTF concluded that the evidence is insufficient to assess the balance of benefits and harms of screening for T2D in children and adolescent [19]

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The acetoacetate is activated to acetoacetyl-CoA via the action of the mitochondrial ketone body utilization enzyme, succinyl-CoA:3-oxoacid-CoA transferase (SCOT) which is encoded by the OXCT1 (3-oxoacid-CoA transferase 1) gene

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