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To fuel the TCA cycle, glutamate is metabolized to alpha-ketoglutarate ( -KG) by glutamate dehydrogenase (GDH)

Contents show Glutathione (GSH) is often called the master antioxidant because of its critical and wide-ranging role in maintaining cellular health and protecting the body from oxidative damage

In addition, it is more effective to treat center-involved diabetic macular edema than photocoagulation surgery and has become the first-line therapy for diabetic macular edema

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PAG acts as a downstream switchboard coordinating pain modulation and innate action patterns

For this reason, the subcutaneous route remains the only clinically validated method of administration