On the one hand, ID represents a major cause of hypothyroidism worldwide, and it also favors the development of goiter and thyroid nodules [6, 17, 23]
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A deficiency in B12 can lead to a significant decrease in energy and exercise tolerance, along with fatigue
However, such a reported increase in autoimmunity after iodine supplementation appears to be largely transient and not associated with a long-term increase in thyroid dysfunction in most studies [7, 25, 26, 28]
