It primarily affects the joints, causing pain, stiffness, and swelling
In addition to xenobiotic detoxification through glutathione conjugation, GSTs also play a key role in the synthesis and metabolism of endogenous compounds, redox homeostasis and cellular signalling 1,2
Researchers are still looking for its potential role in the treatment of certain diseases caused by oxidative stress
Nitric oxide, lipid peroxidation products, and antioxidants in primary fibromyalgia and correlation with disease severity
A study involving aged mice found that spermidine supplementation reduced cardiac hypertrophy and improved left ventricular function
doi: 10.1073/pnas.011513098 204 OConnorTGWinterMAHunnJCarnahanJPressmanEKGloverVet al