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Having said that, GSH-based medication has also been successfully employed to protect against cisplatin induced nephrotoxicity
J., and Croce, C
This binding transcriptionally upregulates the expression of a series of key genes, including GCLC, GCLM (the light chain of GCLC), and xCT (system xc, responsible for cysteine uptake), thereby increasing GSH synthesis and cysteine uptake, thereby strengthening the cell's antioxidant defenses
Key evidence: A pilot RCT by Kumar et al
The influence of polymorphisms of glutathione S -transferases M1 and M3 on the development of human urothelial cancer
To date, clinical trials involving MenSCs have primarily evaluated their therapeutic effects in diseases such as multiple sclerosis, H7N9 influenza virus infection, severe COVID-19, Ashermans syndrome, and ovarian insufficiency (Zhong et al., 2009
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