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Related article : Naltrexone: LDN and Your Genes Saffron (TNF): Saffron has been shown in studies to modulate TNF-alpha levels, thus impacting chronic inflammation.[ref] It has been shown to reduce fatigue in autoimmune disease patients.[ref] Luteolin (PTPN22 variant, TNF variant): Luteolin has been shown to decrease elevated TNF levels significantly.[ref] Related article : Read all about luteolin

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