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doi: 10.1038/nrendo.2017.93 15 WongSHannah-ShmouniFSinclairGSirrsSDahlMMattmanA

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In addition, MLC phosphorylation or activation of other kinases triggers the opening of TJ proteins (including ZO-1 and claudin-1), which can be reversed by adding an inhibitor of MLC phosphorylation [57]

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By supporting the whole antioxidant cycle, you ensure that no single nutrient is overwhelmed