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Psychiatry 115 KeszyckiR.RodriguezG.LocciA.OrellanaH.HaupfearI.DominguezS.et al (2021)

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matrix that is insoluble, typically a polymer like as a chemically modified polyacrylamide or agarose to introduce functional groups that are reactive, the ligand can react, forming stable covalent bonds(4) This particular method is known as the most precise and efficient method for protein purification

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