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When one is missing, the whole system gets backed up

However, implementation of eryptosis assays in nanotoxicology can be limited by the lack of a generally accepted single eryptosis marker and the requirements to use several markers simultaneously, their lower cost-effectiveness compared to the hemolysis assays, and the availability of the equipment, since eryptosis detection is primarily flow cytometry-based

10.1038/s41392-021-00679-0 Signal Transduct Target Ther

This interval reflects copper's hepatic half-life: newly absorbed copper redistributes between albumin-bound, ceruloplasmin-bound, and free pools over approximately 2 to 4 weeks [4]

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