Panczenko-Kresowska B, Ziemlaski S, Rudnicki S, Wojtulewicz L, Przepirka M
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Kannappan et al[59] have shown that FRD augment nitrosothiols in the plasma, liver and skeletal muscle
These physiological perturbations can interact with cardiovascular phenotypes and prothrombotic states to play a significant role in stroke recurrence, functional outcome (Arboix, 2015), and outcome with pharmacological intervention with tissue plasminogen activator (tPA) (Seet et al., 2014)
Under basal conditions, CGS is downregulated, which would curtail cystathionine production 32
However, human clinical data on these wider applications are still preliminary