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When fatty acids reach the mitochondria, they are converted into usable fuel

Rapamycins Modulation of Metabolism Rapamycin was initially discovered as an antifungal metabolite from the bacteria Streptomyces hygroscopicus found in soil on Easter Island

Aging cell 2010;9, 667-684

However, alternative reactions have been identified that allow connectivity between the metabolites of the TCA cycle 30

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