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The results of these two behavioral tests showed that H1d and H3d mice did not experience cognitive decline, while H7d and H14d mice showed a significant weakening in novel object recognition and impaired spatial memory abilities (Fig

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Importantly, the sulfate groups of heparin also make hydrogen bonds with several positively charged residues in an extended loop of c-MET II-IPT1, such as Arg592, Lys595, and Lys599 (Fig

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