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Topical creams, transdermal preparations, oral mucosal products are permitted

*Correspondence: Haibo Lu, [email protected]

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In particular, the PI3K-Akt signaling pathway (hsa04151) shows a higher number of connections (degree = 38), which includes the target genes VEGFA, MAPK3, AKT1, MAPK1, CREB1, EGFR, ADORA2A, MTOR, and PIK3CG, et al