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THC is distributed and metabolized in a region-specific manner, with highest levels in the hippocampus

During the task, young individuals showed the same negative correlation, but older individuals showed a positive relation with Glx instead, showing a possible age-related adaptation such that, in IPL, higher levels of GSH are associated with a lower inhibitory tone (lower GABA+ or higher Glx)

This increased glutathione level promoted the subjects fat burning and insulin resistance

Despite the rapid development of ferroptosis-inducing agents, therapeutic strategies targeting metabolic vulnerability remain in their infancy

Samples were kept frozen prior analysis

H.DattaJ.KutayH.et al (2009)