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Follow-up work has examined GHK-Cu's activity on matrix metalloproteinases, proteoglycan synthesis, and glycosaminoglycan production in the dermal extracellular matrix (Simeon et al., Life Sci, 2000

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While some in-vitro (test tube) and animal studies suggest that copper peptides may act as a mild DHT blocker by inhibiting the 5-alpha reductase enzyme, it is important to note that clinical human data is still evolving, and it is not as potent as prescription DHT blockers (like Finasteride)

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