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Dietary supplements are regulated differently than pharmaceutical drugs under FDA oversight

& Garg, R

doi: 10.1016/j.jtho.2017.07.008

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In the presence of differentiation stimuli, abnormal protein folding in the ER activates the unfolded protein response (UPR) signaling, which can be alleviated by global translational attenuation, induction of molecular chaperones, misfolded protein degradation by endoplasmic reticulum-associated degradation (ERAD), and apoptosis (63)

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