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via the activation of Nrf2 pathway and Sirtuin-3-FoxO3a pathway in AKI and CKD models (Xu et al., 2012

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Consequently, it is imperative to initiate pharmacological treatment in elderly patients with the lowest effective dose, with the possibility of gradually titrating the dosage upwards as deemed necessary (Zhou et al., 2008b)

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Renschler, M