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Cryo EM dynamics analysis and post-3D classification of CTR:Cagri/CagriBB complex 3D variability analysis (3DVA) implemented in cryoSPARC v4.4.1 29,39 was performed to interrogate and visualize the dynamics in the complexes as previously described 25

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Apolipoprotein E genotyping was performed using DNA isolated from blood cells and carried out as previously described.3 Total plasma homocysteine concentrations were determined with the use of high-performance liquid chromatography with fluorometric detection.4 The coefficient of variation for this assay was 9%

Barkas, F., Liberopoulos, E., Kei, A