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Full Staggered Titration Schedule Recommended staggered co-titration across 24 weeks Phase Reta initiation Weeks 1-4 Retatrutide 2 mg/week Cagrilintide Not started Notes Confirm retatrutide GI tolerance first

Ceramide NP: Strengthens the skin barrier and maintains moisture

Jadhav et al., 2006

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These include, (but not limited to) more physical energy, mental alertness and stamina for everyday tasks, improved sleeping patterns, feeling emotionally brighter/happier, better short-term memory, finding it easier to exercise and lose weight, less frequency in urination and improved bladder continence