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Davioud-Charvet E, Delarue S, Biot C, Schwobel B, Boehme CC, Mussigbrodt A, Maes L, Sergheraert C, Grellier P, Schirmer RH and Becker K

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The activity of TAK-062 was not affected when participants were pretreated with proton pump inhibitors, which are commonly used by people with celiac disease and alter the acidity of the stomach

the study shows that cysteine residues in HP1021 are easily oxidized under cellular and laboratory conditions

Long-term safety data remains limited for both routes, but available studies suggest excellent tolerability