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Oxidative stress in hepatitis C virus-human immunodeficiency virus co-infected patients

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A candidate for a potential glutathione-scaffold residue was identified using the following selection criteria: The residue should be rather conserved in enzymatically active in contrast to inactive glutaredoxins and have a charged side chain to ensure a strong ionic glutathione interaction (Fig

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Thus, cholinergic neurotransmission and ACh-dependent regulation of non-neuronal cells employ ThDP coenzyme function for ACh synthesis and non-coenzyme action of thiamine in ACh signaling