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An increasing body of evidence suggests that these features may be modulated by sex-related differences

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The index variant is in near perfect linkage disequilibrium ( r 2 = 0.99) with a missense variant within GIPR (rs1800437, P = 5.1 10 9

Abrogation of cholesteryl ester accumulation via enzymatic inhibition or depletion of ACAT1 was identified as a potent therapeutic strategy to intercept cancer progression and tumor metastasis in orthotropic mouse model of pancreatic cancer