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The -hydroxyl of carnitine is acylated so that acyl-coenzyme A (acyl-CoA), which cannot directly cross the inner mitochondrial membrane, can be transported into the mitochondrial matrix and then participate in -oxidation to produce ATP

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In a controlled clinical trial, 16 gallstone patients scheduled for cholecystectomy were given 500 mg of supplemental vitamin C four times daily for two weeks before surgery

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How drug photodegradation studies led to the promise of new therapies and some fundamental carbanion reaction dynamics along the way