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Most surgeons ask patients to stop all supplements 24 to 48 hours before surgery

For further information on safer colchicine prescribing, see: bpac.org.nz/bpj/2014/september/safer-prescribing.aspx (published in 2014

Additionally, changes in the microenvironment, such as redox state, altered pH, and the presence of reactive oxygen species (ROS) at the pathophysiological sites, can act as sensitive stimuli to trigger drug release in those areas

doi: 10.1124/pr.112.005660, 124

[Abstract]2025 Mar 5;16(1):111

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