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doi: 10.3389/fpsyt.2022.880568 41 DiGiulioDB

Preclinical (animal) data Rodent studies suggest BPC-157 may: Promote blood vessel growth Enhance tendon fibroblast activity Reduce inflammation Protect gastrointestinal tissues However, these findings: Use doses far above any human equivalent Use controlled laboratory injuries Do not predict human efficacy 2

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This is the first trial to demonstrate a significant cardiovascular benefit of a dual GLP-1/GIP agonist in HFpEF