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Comparison of herniated, degenerated, and scoliotic (control) discs Differences between non-degenerated (control) and herniated tissues were similar to differences (described above) between constrained and unconstrained explants (Figs

Outcome measures include biomechanical tensile strength testing of repaired tissue, histological scoring of collagen fiber organization, and immunohistochemical staining for fibroblast and endothelial cell markers

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These cardiovascular benefits may relate to the peptide's stress-reducing effects, since chronic stress contributes to hypertension and cardiac dysfunction