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Importantly, at study completion, 5A-1MQ-treated mice had a lower fat mass than the obese WD controls and their vehicle-treated counterparts and were not significantly different (with FDR correction) from the LD control mice (Fig

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Apoptosis inhibitor of macrophage (AIM), also called CD5 antigen-like (CD5L), is a 36 kDa soluble protein that belongs to the SRCR superfamily Group B with three head-to-tail linked SRCR domains, mainly expressed by tissue-resident macrophages in the liver as well as lymphoid and inflamed tissues 3,4

stabilising it could reduce the chronic inflammatory burden in PMOS

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