Nat Med 30 , 315318 (2024)
Chronic illness, autoimmune dysfunction, frequent infections these peptides retrain immune function rather than suppressing it
UC involves the colonic mucosa in a continuous distribution from the anal verge to all or part of the colon CD involves transmural patchy inflammation with intervening normal mucosa and can occur anywhere in the gastrointestinal tract from the mouth to the anus Indeterminate colitis has features of UC and CD EIMs can be present in all forms of IBD Epidemiology Onset of IBD is most frequent among adolescents, with a peak incidence between ages 15 and 25 years
S2CID 919401
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