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Keratinocytes interact with immune cells recruited to the site of inflammation and increase the expression of adhesion molecules, which enables immune cells to adhere to the vascular endothelium ( According to the literature, oxidative and nitrosative stress plays a role in the progression of chronic spontaneous urticaria (CSU) ( Table 1 ) (164, 165)

Individual variability : The optimal dosage can vary significantly between individuals due to genetic factors, overall health status, and other variables

Chow JM, Shen SC, Huan SK, Lin HY, Chen YC

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Insights into a possible role of glucagon-like peptide-1 receptor agonists in the treatment of depression

(1971) Side effects of organo- phosphorus compounds: delayed neurotoxicity