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Angiogenesis Enhancement Damaged tissue requires increased blood flow to receive the oxygen and nutrients necessary for repair

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In most cases, they are loss-of-function mutations of KEAP1 or gain-of-function mutations of NRF2 , causing the persistent stabilization of NRF2

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In addition to classical regulatory mechanisms, new regulatory factors for ferroptosis have been discovered in recent years, such as the P53 pathway, the activating transcription factor (ATF)3/4 pathway, Beclin 1 (BECN1) pathway, and some non-coding RNA

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