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Consistently, early therapeutical intervention with biologics, i.e., TNF- inhibitors, is supported by national and international guidelines for the treatment of patients with moderate-to-severe disabling CD

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If nausea persists beyond 3-4 weeks on a stable dose, consider reducing to the previous dose level and attempting re-escalation more gradually after 4-6 weeks

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Timing consistency allows your GI tract to adapt to a predictable rhythm, which reduces nausea severity over time