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JCI Insight 4:e123182

This pathway plays a vital role in maintaining cellular homeostasis, particularly in the heart, where protein misfolding and aggregation can have severe consequences for cardiac function

Their functional enrichment analyses linked these genes to mRNA metabolic processes, immune cell regulation, and RNA transport pathways, confirming their potential role in OA pathogenesis and immune-mediated joint degradation (Huo et al., 2025)

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J., Alves-Lopes, R., Montezano, A

Nitric oxide, observed during the inflammatory phase of wound healing, has been shown to compromise collagen accumulation, which is a crucial process in skin health