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According to the Mayo Clinic, parenteral vitamin B12 therapy is clinically indicated for treating deficiency caused by pernicious anemia, gastrointestinal disorders such as tropical sprue, and conditions resulting in malabsorption like pancreatic insufficiency

This includes finding at-risk groups, using preventive tests, and making lifestyle changes to better absorb nutrients

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These signs include: Less fatigue and more energy Neurological symptoms like numbness or tingling getting better Brain function getting sharper Gastrointestinal problems getting better Clinical improvement often comes before lab results show big changes

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