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In contrast, taking glutathione by mouth (as pills or liquids) is far less efficient because the compound is largely broken down in the gut before it ever reaches the cells

But the 2022 Cochrane review rates the evidence low-certainty overall, selenium helps mainly where status is low, not as a universal top-up

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Not recommended for children, pregnant

There are many unknowns, including dose-response in humans, interactions with other fertility treatments, and differences at various stages of conception including gametogenesis, implantation, and gestation