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The concept of this decentralized or virtual trial approach has been growing slowly ever since and has accelerated significantly following the recent SARS-CoV-2 pandemic, where restrictions in face-to-face approaches and increased hospital burden forced researchers to investigate alternative approaches to the standard site-based, centralized research format

doi:10.1371/journal.pone.0119479 41

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J Cardiothorac Vasc Anesth

First, we performed extracellular flux analysis to assay the mitochondrial complex-dependent OCR profile in saponin-permeabilized Gclc fl/fl and Gclc fl/fl Mb1-Cre + FoB

Noticeable changes around week five