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Enebo, L., Berthelsen, K., Kankam, M., Lund, M., Rubino, D., Satylganova, A., & Lau, D

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Quick Answer: Dihexa is a synthetic small molecule developed at Washington State University from angiotensin IV research, often called a peptide despite being more accurately described as a peptidomimetic Despite being commonly called a peptide, Dihexa contains chemical modifications that make it more accurately described as a peptidomimetic small molecule

47,48,49 Of note, the CD38 and SARM1 display K m for NAD + in a markedly low micromolar range (1525 M)

Using macrophages, Lin et al

Bennett JP Jr, Keeney PM (2020) Alzheimers and parkinsons brain tissues have reduced expression of genes for mtDNA OXPHOS proteins, mitobiogenesis regulator PGC-1 protein and mtRNA stabilizing protein LRPPRC (LRP130)