and a single C-terminal Cys (clade R- C
Whether one is better than the other depends on your health and what your doctor advises
Feng L, Cheah IKM,Ng MMX, Li J,Chan SM, et al
It is intended exclusively for in vitro studies, biochemical assays, and preclinical experimental models conducted by qualified research personnel
Ohshimura et al
5-FU administration for 24 h can increase the expression level of bound TS in HCT116 and HT29 CRC cells and inhibit the expression of p53, thereby tolerating 5-FU ( In BC, 5-FU combined with QUE further promoted the apoptosis of MCF-7 cells by increasing the expression of Bax, Caspase-9, and p53 genes and decreasing the expression of bcl-2 genes, indicating that QUE could enhance the sensitivity of 5-FU to BC ( In conclusion, the present study suggests that QUE sensitizes CRC and BC cells to 5-FU by regulating the expression of apoptotic proteins ( Table 1 )