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Erastin, a well-known ferroptosis inducer, inhibits system Xc and blocks voltage-dependent anion channels, thereby activating p53 and inducing ferroptosis [149, 150]

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Data were collected using EPU EM software (Thermo Fisher Scientific) for all samples

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It is, in effect, the body's own copper-transport and tissue-signaling peptide: a simple three-amino-acid chain (glycine-histidine-lysine) with a very high natural affinity for copper ions, forming a stable complex that is easily studied and reproduced synthetically for laboratory use

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